Can-SOLVE CKD Network Annual Meeting 2021 project video

Project lead: Dr. Chris McIntyre

One key function of the kidney is to balance the level of sodium in our bodies by getting rid of it through urine. There have been studies that show when kidney function is impaired, the extra sodium may end up on skin, muscle or bones, causing inflammation. There is a potential link between sodium and inflammation that may explain the symptoms that dialysis patients experience such as itch, low energy and restless legs. This study will try to examine sodium deposition in the skin, muscle and bones of patients with different kidney function and different dialysis modalities and its association with symptoms.

Can-SOLVE CKD Network Annual Meeting 2021 visual abstract

visual abstract PDF version



Influence of Dialysate Sodium Prescription on Skin and Muscle Sodium Concentration.

Lemoine S, Salerno FR, Akbari A, McIntyre CW.Am J Kidney Dis. 2021 Jul;78(1):156-159. doi: 10.1053/j.ajkd.2020.11.025. Epub 2021 Jan 9.PMID: 33428998 No abstract available.
Qirjazi E, Salerno FR, Akbari A, Hur L, Penny J, Scholl T, McIntyre CW.Nephrol Dial Transplant. 2020 Apr 6:gfaa036. doi: 10.1093/ndt/gfaa036. Online ahead of print.PMID: 32252091
Lemoine S, Salerno FR, Akbari A, McKelvie RS, McIntyre CW.Circ Cardiovasc Imaging. 2021 Nov;14(11):e012910. doi: 10.1161/CIRCIMAGING.121.012910. Epub 2021 Nov 16.PMID: 34784242
Penny JD, Salerno FR, Akbari A, McIntyre CW.Hemodial Int. 2021 Jan;25(1):E10-E14. doi: 10.1111/hdi.12885. Epub 2020 Sep 29.PMID: 32996258
Akbari A, Lemoine S, Salerno F, Marcus TL, Duffy T, Scholl TJ, Filler G, House AA, McIntyre CW.Radiology. 2022 May;303(2):384-389. doi: 10.1148/radiol.211238. Epub 2022 Feb 8.PMID: 35133199 Clinical Trial.
Filler G, Geda R, Salerno F, Zhang YC, de Ferris MED, McIntyre CW.Pediatr Nephrol. 2021 Nov;36(11):3621-3626. doi: 10.1007/s00467-021-05213-6. Epub 2021 Aug 24.PMID: 34427794
Filler G, Salerno F, McIntyre CW, de Ferris MED.Curr Pediatr Rep. 2021;9(4):110-117. doi: 10.1007/s40124-021-00249-6. Epub 2021 Sep 18.PMID: 34567839 Free PMC article. Review.