Project Overview

One key function of the kidney is to balance the level of sodium in our bodies by getting rid of it through urine. There have been studies that show when kidney function is impaired, the extra sodium may end up on skin, muscle or bones, causing inflammation. There is a potential link between sodium and inflammation that may explain the symptoms that dialysis patients experience such as itch, low energy and restless legs. This study will try to examine sodium deposition in the skin, muscle and bones of patients with different kidney function and different dialysis modalities and its association with symptoms.

Evaluation of sodium deposition in soft tissues of patients with kidney disease and its association with patient symptomatology

Project lead(s):

Dr. Christopher McIntyre

Research theme(s):

Symptom Management

Project video

Visual Abstract

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Publications

  • Comparison of Clinical and Social Characteristics of Canadian Youth Living with Type 2 and Type 1 Diabetes

    Canadian Journal of Diabetes

    Carino M, Elia Y, Sellers E, Curtis J, McGavock J, Scholey J, Hamilton J, Clarson C, Pinto T, Hadjiyannakis S, Mertens L, Samaan MC, Ho J, Nour M, Panagiotopoulos C, Jetha M, Gabbs M, Mahmud FH, Wicklow B, Dart A

    Research Project: iCARE,AdDIT

    Keywords: type 2 diabetes, Type 1 diabetes

  • Evaluation of novel glomerular filtration rate estimation equations in adolescents and young adults with type 1 diabetes

    Journal of Diabetes and its Complications

    Gaebe K, White CA, Mahmud FH, Scholey JW, Elia YT, Sochett EB, Cherney DZ

    Research Project: AdDIT

    Keywords: Glomerular Filtration Rate, Type 1 diabetes

  • Relationship between serum inflammatory markers and vascular function in a cohort of adolescents with type 1 diabetes

    Cytokine

    Sochett E, Noone D, Grattan M, Slorach C, Moineddin R, Elia Y, Mahmud FH, Dunger DB, Dalton N, Cherney D, Scholey J, Reich H, Deanfield J.

    Research Project: AdDIT

    Keywords: Diabetes

  • Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with Type 1 diabetes mellitus

    American Journal of Physiology – Renal Physiology

    Lovshin JA, Škrtić M, Bjornstad P, Moineddin R, Daneman D, Dunger D, Reich HN, Mahmud F, Scholey J, Cherney DZI, Sochett E

    Research Project: AdDIT

    Keywords: Diabetes, Cardiovascular Disease

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