Project Overview

Indigenous people have a higher risk of CKD and kidney failure compared to the non-Indigenous population. This may be due to increased rates of diabetes, particularly in children, which can lead to CKD in early adulthood. In addition, many Indigenous people live in rural communities where there is limited access to doctors and appropriate health care services. As a result, many community members have to leave behind their homes and families in order to receive treatment. Therefore it is very important to diagnose CKD early, or catch those individuals at the highest risk, so that early treatments can help prevent CKD or stop the progression to kidney failure.

Our team will conduct a screening initiative in Indigenous communities in five provinces across Canada. Using mobile lab equipment, screening teams will travel to communities and test for CKD and its risk factors, including diabetes and high blood pressure. This information will be used to determine an individual’s risk of CKD, and each person will receive a treatment plan that is tailored to their risk. This may include counseling, treatment recommendations, an appointment with a doctor, or direct referral to a kidney specialist. This study will help to provide evidence to help develop a permanent CKD surveillance system in all Indigenous communities across Canada. This will help to decrease the burden of CKD and kidney failure in these communities. With correct treatment and continued follow-up, the number of Indigenous people with CKD will decline and fewer patients will progress to kidney failure requiring dialysis.

Kidney Check: Identifying kidney disease and diabetes in Indigenous communities

Project lead(s):

Dr. Aminu Bello

Patient lead(s):

Cathy Woods

Research theme(s):

Indigenous Health

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Project video

Visual Abstract

Kidney Check visual abstract

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Publications

  • Tissue Sodium Storage in Patients With Heart Failure: A New Therapeutic Target?

    Circulation: Cardiovascular Imaging

    Lemoine S, Salerno FR, Akbari A, McKelvie RS, McIntyre CW

  • Burden of mental health symptoms and perceptions of their management in in-centre hemodialysis care: a mixed methods study

    Journal of Patient-Reported Outcomes

    Schick-Makaroff K, Wozniak LA, Short H, Davison SN, Klarenbach S, Buzinski R, Walsh M, Johnson JA

  • Mapping the Edmonton Symptom Assessment System-Revised: Renal to the EQ-5D-5L in patients with chronic kidney disease

    Quality of Life Research

    Wen J, Jin X, Al Sayah F, Short H, Ohinmaa A, Davison SN, Walsh M, Johnson JA

  • Patient, Caregiver, and Provider Perspectives on Improving Information Delivery in Hemodialysis: A Qualitative Study

    Canadian Journal of Kidney Health and Disease

    Ferreira da Silva P, Talson MD, Finlay J, Rossum K, Soroka KV, McCormick M, Desjarlais A, Vorster H, Fontaine G, Sass R, James M, Sood MM, Tong A, Pannu N, Tennankore K, Thompson S, Tonelli M, Bohm C

  • Voicing Individual Concerns for Engagement in Hemodialysis (VOICE-HD): A Mixed Method, Randomized Pilot Trial of Digital Health in Dialysis Care Delivery.

    Canadian Journal of Kidney Health and Disease

    Thompson S, Schick-Makaroff K, Bello A, Tonelli M, Wiebe N, Buzinski R, Courtney M, Szigety S, Shah N, Bohm C

    Research Project: Triple I

  • Program Report: Can-SOLVE CKD Network Presents an Inclusive Method for Developing Patient-Oriented Research Tools

    Canadian Journal of Kidney Health and Disease

    Getchell LE, Fowler E, Reich M, Allu S, Boucher C, Burns K, Desjarlais A, L'Esperance A, Elliott M, Robinson-Settee H, Chiu HH, Rosenblum ND, Settee C, Murdoch A, Dew S, Green A, Franson L, Bernstein E, Sparkes D, Turner C, Fernandez N, Sapir-Pichhadze R

  • Functional Sodium MRI Helps to Measure Corticomedullary Sodium Content in Normal and Diseased Human Kidneys

    Radiology

    Akbari A, Lemoine S, Salerno F, Marcus TL, Duffy T, Scholl TJ, Filler G, House AA, McIntyre CW

    Research Project: NaMRI

  • Management of severe polyuria in idiopathic Fanconi syndrome

    Pediatric Nephrology

    Filler G, Geda R, Salerno F, Zhang YC, de Ferris MED, McIntyre CW

    Research Project: NaMRI

  • Animal, Human, and 23Na MRI Imaging Evidence for the Negative Impact of High Dietary Salt in Children

    Current Pediatric Reports

    Filler G, Salerno F, McIntyre CW, de Ferris MED

  • Partnering with Patients to Enhance Access to Kidney Transplantation and Living Kidney Donation

    Healthcare Quarterly

    Naylor KL, McKenzie SQ, Garg AX, Yohanna S, Sontrop JM

    Research Project: Living Donor

  • Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial

    Canadian Journal of Kidney Health and Disease

    Yohanna S, Wilson M, Naylor KL, Garg AX, Sontrop JM, Belenko D, Elliott L, McKenzie S, Macanovic S, Mucsi I, Patzer R, Voronin I, Lui I, Blake PG, Waterman AD, Treleaven D, Presseau J

    Research Project: Living Donor

  • A Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) in Patients With Chronic Kidney Disease: Clinical Research Protocol of a Cluster-Randomized Clinical Trial

    Canadian Journal of Kidney Health and Disease

    Yohanna S, Naylor KL, Mucsi I, McKenzie S, Belenko D, Blake PG, Coghlan C, Dixon SN, Elliott L, Getchell L, Ki V, Nesrallah G, Patzer RE, Presseau J, Reich M, Sontrop JM, Treleaven D, Waterman AD, Zaltzman J, Garg AX

    Research Project: Living Donor

  • An eHealth self-management intervention for adults with chronic kidney disease, My Kidneys My Health: a mixed-methods study

    CMAJ Open

    Donald M, Beanlands H, Straus S, Smekal M, Gil S, Elliott MJ, Harwood L, Waldvogel B, Delgado M, Sparkes D, Tong A, Grill A, Novak M, James MT, Brimble KS, Tu K, Hemmelgarn BR

  • Risk of CKD Progression and Quality of Care Indicators in the Primary Care Setting

    American Journal of Kidney Diseases

    Yuen J, Harasemiw O, Singer A, Bello A, Ronksley PE, Bohm C, Drummond N, Tangri N

    Research Project: KFRE

     

  • Addressing Inequities in Kidney Care for Indigenous People in Canada

    Journal of the American Society of Nephrology

    Harasemiw O, Komenda P, Tangri N

  • Impact of COVID-19 Pandemic on Adolescents and Young Adults Living With Type 2 Diabetes

    Canadian Journal of Diabetes

    Marylin Carino, Zoe Quill, Melissa Gabbs, Elizabeth Sellers, Jill Hamilton, Teresa Pinto, Mary Jetha, Josephine, Onalee Garcia Alecio, Allison Dart, Brandy Wicklow

    Research Project: iCARE

  • Relationship between serum inflammatory markers and vascular function in a cohort of adolescents with type 1 diabetes

    Cytokine

    Sochett E, Noone D, Grattan M, Slorach C, Moineddin R, Elia Y, Mahmud FH, Dunger DB, Dalton N, Cherney D, Scholey J, Reich H, Deanfield J.

    Research Project: AdDIT

    Keywords: Diabetes

  • Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with Type 1 diabetes mellitus

    American Journal of Physiology – Renal Physiology

    Lovshin JA, Škrtić M, Bjornstad P, Moineddin R, Daneman D, Dunger D, Reich HN, Mahmud F, Scholey J, Cherney DZI, Sochett E

    Research Project: AdDIT

  • Content and quality of websites for patients with chronic kidney disease: An environmental scan

    Canadian Journal of Kidney Health and Disease

    Smekal M, Gil S, Donald M, Beanlands H, Straus S, Herrington G, Sparkes D, Harwood L, Tong A, Grill A, Tu K, Waldvogel B, Large C, Large C, Novak M, James M, Elliott M, Delgado M, Brimble S, Samuel S, Hemmelgarn BR.

  • Development and Validation of Nine Deprescribing Algorithms for Patients on Hemodialysis to Decrease Polypharmacy

    Canadian Journal of Kidney Health and Disease

    Lefebvre MJ, Ng PCK, Desjarlais A, McCann D, Waldvogel B, Tonelli M, Garg AX, Wilson JA, Beaulieu M, Marin J, Orsulak C, Lloyd A, McIntyre C, Feldberg J, Bohm C, Battistella M

    Research Project: STOP Med-HD

  • Patient Perspectives on Integrating Risk Prediction Into Kidney Care: Opinion Piece

    Canadian Journal of Kidney Health and Disease

    Sparkes D, Lee L, Rutter B, Harasemiw O, Thorsteinsdottir B, Tangri

    Research Project: KFRE

  • Patient-reported outcome measures in the care of in-centre hemodialysis patients

    Journal of Patient-Reported Outcomes

    Davison S, Klarenbach S, Manns B, Schnick-Makaroff K, Buzinski R, Corradetti B, Short H, Johnson J

  • Development and Preliminary Psychometric Testing of an Adult Chronic Kidney Disease Self-Management (CKD-SM) Questionnaire

    Canadian Journal of Kidney Health and Disease

    Smekal MD, Donald M, Beanlands H, Straus S, Herrington G, Waldvogel B, Sparkes D, Delgado M, Bello A, Hemmelgarn BR

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