Project Summary
Living donor kidney transplants offer better outcomes and lower costs than dialysis, but access remains uneven, and the process can be daunting. The Living Donor Kidney Transplantation project aims to improve access to living donor transplants by identifying barriers, streamlining the donor assessment process, and creating tools for health system improvement.
Through initiatives like the Transplant Ambassador Program (TAP) and a one-day donor assessment clinic, the team is helping more patients navigate the path to transplant—while expanding access in Ontario and beyond.
Why This Work Matters
For patients with kidney failure, a transplant from a living donor can mean more years of life and freedom from dialysis. Yet many patients never receive one, due to health system barriers, resource constraints, and inequities in access. This project addresses those gaps by redesigning the donor assessment process and supporting patients through peer mentorship.
The result is faster evaluations, better-informed decisions, and a more equitable, patient-centred path to the best possible kidney care.
Project Objectives
- Increase access to living donor kidney transplants by identifying system barriers and implementing targeted quality improvement interventions.
- Improve the efficiency of donor evaluations through innovations like the One-Day Living Donor Assessment Clinic.
- Expand the Transplant Ambassador Program (TAP) to support patients and potential donors with peer-led education and emotional support.
- Promote equity in access to living kidney donation for underserved populations.
- Support system-wide adoption of living donation improvements across Ontario and other provinces.
Recent Activities & Progress
- Hosted a national consensus conference with ~100 experts, generating 35 recommendations to improve the living donor evaluation process across Canada.
- Advanced health equity by developing protocols to address transplant barriers in Northern Ontario.
- Expanded TAP to 210+ ambassadors (26 languages), 170+ patient subscribers, and new outreach in Atlantic Canada.
- Delivered 13 educational webinars and presentations nationwide, including events in French and contributions to major nephrology and transplant forums.
- Scaled a one-day clinic for donors, now active at three out of five adult kidney transplant centres in Ontario, with knowledge-sharing across Canada. Started a one-day referral clinic for transplant recipients.
Living Donor Kidney Transplantation
Project lead(s):
- Dr. Kyla Naylor, Assistant Professor (Schulich School of Medicine & Dentistry, Western University)
- Dr. Seychelle Yohanna, Professor and Transplant Nephrologist (McMaster University and St. Joseph’s Healthcare Hamilton)
- Dr. Amit Garg, Professor and Nephrologist (Schulich School of Medicine & Dentistry, Western University)
Patient lead(s):
- Susan McKenzie (Ontario)
Research theme(s):
Transplantation
Project Video
Publications
Efficiency of the living kidney donor evaluation:
- Initiating Maintenance Dialysis Before Living Kidney Donor Transplantation When a Donor
- Healthcare Costs for the Evaluation, Surgery, and Follow-Up Care of Living Kidney Donors
- The Efficiency of Evaluating Candidates for Living Kidney Donation: A Scoping Review
- Duration of Living Kidney Transplant Donor Evaluations: Findings From 2 Multicenter Cohort Studies
- A RAND-Modified Delphi on Key Indicators to Measure the Efficiency of Living Kidney Donor Candidate Evaluations
- Potential implications of a more timely living kidney donor evaluation
- Evaluating multiple living kidney donor candidates simultaneously is more cost-effective than sequentially
Quality improvement intervention to improve access to kidney transplantation and living donation
- Increasing the Rate of Living Donor Kidney Transplantation in Ontario: Donor- and Recipient-Identified Barriers and Solutions.
- A Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) in Patients With Chronic Kidney Disease: Clinical Research Protocol of a Cluster-Randomized Clinical Trial
- Protocol for a Process Evaluation of the Quality Improvement Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) Cluster-Randomized Clinical Trial.
- Partnering with Patients to Enhance Access to Kidney Transplantation and Living Kidney Donation.
- Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD): Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial.
- Effect of a Novel Multicomponent Intervention to Improve Patient Access to Kidney Transplant and Living Kidney Donation The EnAKT LKD Cluster Randomized Clinical Trial
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